417 Uncommon Occupational Allergy to Rice: as a Food Allergen
نویسندگان
چکیده
investigated by immunoblot with serum from individuals sensitized to anisakis or shrimp. IgE binding patterns in the immunoblots were used for the identification of major Anisakis allergens, which were analysed by mass spectrometry-based proteomics in ESI-Orbitrap, after separation on SDS-gel. Results: Four new allergen candidates were identified. The first identified allergen was enolase, which is related to the cockroach allergen enolase. The other allergens were Heat Shock Protein-70 (HSP 70), tubulin, and glutathion-S-transferase, which are also present as allergens in house dust mite. Conclusions: Here we describe the identification of 4 novel IgE binding allergens in anisakis. The allergens might explain IgE cross-reactivity between anisakis and house dust mite or cockroach.
منابع مشابه
Management of Food Allergy
Although food allergy is a major public health problem, currently there is no effective and safe treatment except to avoid the foods .But the need for new options is critical now as the number of children diagnosed with food allergies rises. Avoiding the offending allergen in the diet is the primary treatment of food allergy. Once a food to which the patient is sensitive has been identified, th...
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1. Fiocchi A, Bouygue GR, Restani P, Gaiaschi A, Terracciano L, Martelli A. Anaphylaxis to rice by inhalation. J Allergy Clin Immunol. 2003;111:193--5. 2. Nakase M, Usui Y, Alvarez-Nakase AM, Adachi T, Urisu A, Nakamura R, et al. Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens. Allergy. 1998;53 Suppl.:55--7. 3. Asero R, Amato S, Alfieri B, Folloni ...
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